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Premature Ejaculation Pills: Everything You Need To Know

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Premature ejaculation is something that a lot of men grow out of, but when you're dealing with it, it's never really the most fun thing to go through. Sometimes it can feel embarrassing, or like a let-down for your partner, but it is something that you can work through and change with the right practice, mindset, and understanding.

You can also try many different things to help with your premature ejaculation. It can be a difficult thing to change, but if you're willing to put in the effort it can be done.

Many men turn to premature ejaculation pills. These can be extremely helpful in allowing you to last longer during sex, and there are a variety of different kinds of medications on the market that can help with premature ejaculation.

This article will cover all the different types of medications for premature ejaculation, how they work, what the side effects are, and how to take them.

What Is Premature Ejaculation?

Premature ejaculation is a medical condition that affects men of all ages. It is characterized by a man's inability to control his ejaculation, which leads to him ejaculating sooner than he or his partner would like. In some cases, premature ejaculation can occur before or during intercourse. In other cases, it can occur when a man is not sexually aroused. Premature ejaculation can be a one-time occurrence, or it can happen frequently.


Premature ejaculation is not a permanent medical condition and can be treated. There are a variety of medical treatments available, as well as lifestyle changes that can help to improve a man's ability to control his ejaculation.

Symptoms of Premature Ejaculation

In men, premature ejaculation is defined as ejaculation that occurs sooner than desired, either before or shortly after sexual penetration. While it may occur at any time during sexual arousal, it is most common during the early stages of intercourse.

Symptoms can vary from man to man, and may include:

  • Ejaculation that occurs sooner than desired, either before or shortly after sexual penetration
  • A feeling of anxiety, frustration, or embarrassment
  • Reduced sexual pleasure because of less time available to enjoy sex
  • Reduced satisfaction with sexual intercourse
  • Avoidance of sexual intimacy because of the fear of premature ejaculation

If you are experiencing any of these symptoms, know that you're not alone and that this is something that can be worked through either with medication or practice.

Causes of Premature Ejaculation

Some of the causes of premature ejaculation are:

  • Erectile dysfunction
  • Anxiety
  • Depression
  • Stress
  • Fatigue
  • Relationship problems
  • Guilt

ED and Premature Ejaculation

Erectile dysfunction can cause premature ejaculation, and premature ejaculation can cause erectile dysfunction—making a vicious cycle. When men are unable to sustain an erection, it can cause anxiety. This anxiety can lead to a panic response, causing the release of adrenaline and cortisol. These hormones trigger the ejaculatory response, resulting in premature ejaculation. This relationship is further complicated by the fact that many men who experience erectile dysfunction also experience anxiety about their sexual performance.

It’s important to remember that erectile dysfunction and premature ejaculation are two separate issues. While they may be related, it’s important to seek treatment for both conditions. If you’re experiencing both erectile dysfunction and premature ejaculation, your doctor may prescribe a phosphodiesterase type 5 inhibitors, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra). These medications can help with both conditions by relaxing the muscles in the penis and increasing blood flow.

This may help to improve erectile dysfunction by allowing men to sustain an erection long enough to have sex. It may also help to delay ejaculation. However, these medications may not be right for everyone, and they can have side effects. Be sure to talk to your doctor about all your treatment options.

Anxiety and Premature Ejaculation

As noted, anxiety can be a major factor in both erectile dysfunction and premature ejaculation. In fact, anxiety is one of the most common causes of premature ejaculation. Anxiety about sexual performance can lead to a panic response, causing the release of adrenaline and cortisol. These hormones trigger the ejaculatory response, resulting in premature ejaculation.

Treatment for premature ejaculation caused by anxiety may include counseling, medication, and sexual techniques to delay ejaculation. Be sure to talk to your doctor about all your treatment options.

Talk with your partner about your anxiety, and work together to find ways to ease your anxiety and improve your sexual relationship.

Depression and Premature Ejaculation

Depression is one of the most common psychological conditions, and it can take a toll on every aspect of your life, including your sex life. Depression can cause a loss of interest in sex, difficulty becoming aroused, and erectile dysfunction. Depression can also lead to premature ejaculation.

Depression affects the chemicals in your brain that are responsible for sexual arousal and pleasure. It can also lead to anxiety and stress, which can trigger the release of adrenaline and cortisol. These hormones can cause the ejaculatory response, resulting in premature ejaculation.

Treatment for premature ejaculation caused by depression may include antidepressants, talk therapy, and stress-reduction techniques. If you’re taking antidepressants, your doctor may also prescribe a selective serotonin reuptake inhibitor (SSRI), such as fluoxetine (Prozac), paroxetine (Paxil), or sertraline (Zoloft). These medications can help to delay ejaculation.

SSRIs work by affecting the chemicals in your brain that are responsible for depression and anxiety. They can take several weeks to work, and they can have side effects, such as nausea, headache, and sexual side effects. Be sure to talk to your doctor about all your treatment options.

Stress and Premature Ejaculation

Stress is another common cause of premature ejaculation. When you’re stressed, your body goes into “fight or flight” mode. This triggers a release of hormones, including adrenaline and cortisol. These hormones can cause the muscles in your penis to tense up, making it difficult to sustain an erection. Stress can also lead to anxiety, which can cause the same muscle tension and make it difficult to delay ejaculation.

If stress is a contributing factor to your premature ejaculation, there are several things you can do to manage it. Exercise, relaxation techniques, and therapy can all help to reduce stress. If your stress is due to relationship issues, couples counseling may be helpful.

Fatigue and Premature Ejaculation

Fatigue can be a major cause of premature ejaculation. When you’re tired, your body is under stress, which can lead to a heightened sense of arousal. This can make it more difficult to control your ejaculation. In addition, fatigue can make it difficult to get or maintain an erection.

If you’re experiencing fatigue, there are a few things you can do to help. First, make sure you’re getting enough sleep. It’s also important to eat a healthy diet and to exercise regularly. If you’re still feeling fatigued, your doctor may recommend a medication to help.

Relationship Problems and Premature Ejaculation

Premature ejaculation can be a difficult issue to deal with, both for the man who experiences it and for his partner. It can be a source of great anxiety and can cause problems in a relationship. If you’re struggling with premature ejaculation, it’s indispensable to talk to your partner about it. Open communication can help to reduce anxiety and stress, and it can help you to work together to find a solution.

Relationships can be tricky, stressful, and even downright difficult at times. But if you’re struggling with premature ejaculation, it’s critical to remember that you’re not alone. Many men experience this issue, and there are ways to deal with it. If you’re struggling, talk to your doctor. They can help you to find the cause of your premature ejaculation and may be able to recommend treatment options.

Sometimes, talking with your partner can help. When they know what to expect, it can ease your nerves. Sometimes, you just need a bit of practice. The excitement of sex can sometimes make it difficult to control your ejaculation. But with a bit of time and patience, you may be able to train your body to last longer.

There are also a number of medications that can help to treat premature ejaculation. If you’re interested in trying medication, be sure to talk to your doctor. They can help you to understand the risks and benefits of each option and can prescribe the best medication for you.

How Premature Ejaculation Pills Work

How the medicine works depends on what you use to treat premature ejaculation. ED medications, antidepressants, topical anesthetics, and certain exercises can be used to delay ejaculation.

Premature ejaculation pills can work in a variety of ways. First, they can help to reduce your anxiety level, which may be a contributing factor to your premature ejaculation. (SSRIs and anti-anxiety medications.)

Second, some premature ejaculation pills may help to increase the amount of blood flow to your penis. This increased blood flow can help you to achieve an erection more quickly and also help you to maintain an erection. (ED medications)

Some men find that topical anesthetics help to delay ejaculation. These products work by numbing the penis, which can help to delay ejaculation. However, they don't always work, and they can cause some side effects, such as numbness, tingling, or irritation. If you're interested in trying a topical anesthetic, talk to your doctor about your options.

How SSRIs Treat Premature Ejaculation

SSRIs increase the level of serotonin in the brain. This can have many effects, but one of them is to delay ejaculation. It is thought that by increasing serotonin levels, the body becomes more resistant to sexual stimuli, thus delaying ejaculation.

SSRIs work by inhibiting the reuptake of serotonin in the brain. Serotonin is a neurotransmitter that is responsible for mood and emotion. When levels of serotonin are low, it can lead to depression and anxiety. SSRIs work by preventing the reuptake of serotonin, which means that more serotonin is available for the brain to use. This can have a number of different effects, one of which is delaying ejaculation.

It is thought that SSRIs work by increasing the level of serotonin in the brain. Serotonin is a neurotransmitter that is responsible for mood and emotion. When levels of serotonin are low, it can lead to depression and anxiety. SSRIs work by preventing the reuptake of serotonin, which means that more serotonin is available for the brain to use. This can have a number of different effects, one of which is delaying ejaculation.

Ejaculation happens when the body is stimulated sexually and the brain sends a signal to the genitals to start the process. When someone takes an SSRI, it is thought that the increased level of serotonin in the brain makes the body more resistant to sexual stimulation. This means that it takes longer for the brain to send the signal to the genitals to start the process of ejaculation.

How PDE5 Inhibitors Treat Premature Ejaculation

PDE5 inhibitors are drugs that are used to treat erectile dysfunction. They work by inhibiting the enzyme PDE5, which is responsible for the breakdown of cGMP. cGMP is a substance that is responsible for the relaxation of blood vessels. When PDE5 is inhibited, cGMP levels increase and the blood vessels relax, resulting in an erection.

PDE5 inhibitors can also be used to treat premature ejaculation. In men with premature ejaculation, PDE5 is found in high levels in the corpus cavernosum, the tissue that makes up the erectile tissue in the penis. By inhibiting PDE5, these drugs can increase the levels of cGMP in the corpus cavernosum and delay ejaculation.

Sildenafil (brand name Viagra) is a PDE5 inhibitor that is also used to treat erectile dysfunction. It is not FDA approved to treat premature ejaculation, but it is often used off-label for this purpose. Tadalafil (brand name Cialis) and Vardenafil (brand name Levitra) are also PDE5 inhibitors that are used to treat erectile dysfunction. These drugs have not been studied specifically for the treatment of premature ejaculation, but they are sometimes used off-label for this purpose.

PDE5 inhibitors are generally well tolerated. The most common side effects are headache, flushing, nausea, and dizziness. These drugs can also cause low blood pressure and fainting

Side Effects of Premature Ejaculation Pills

There are a few side effects that may occur when taking premature ejaculation pills. However, they are usually mild and do not last very long.

If Using SSRIs:

  • Nausea
  • Dizziness
  • Headache
  • Diarrhea
  • Insomnia
  • Dry mouth
  • Fatigue
  • Sweating
  • Decreased appetite


If Using ED Medication:

  • Headache
  • Dizziness
  • Nausea
  • Flushing
  • Visual changes


If Using A Topical Anesthetic:

  • Skin irritation
  • Allergic reaction

Other Premature Ejaculation Solutions

The following solutions can help you control premature ejaculation.

1. Tramadol

Tramadol is a medication that is commonly used to treat pain. It is also a medication that can help control premature ejaculation. Tramadol works by inhibiting the reuptake of serotonin and norepinephrine. This helps to delay ejaculation.

Tramadol is not easy to get a prescription for, as it's an opiate. This means it carries the risk of addiction, abuse, and dependence. Tramadol can also cause death when mixed with benzodiazepines. Because of this, Tramadol is not recommended as a first-line treatment for premature ejaculation.


2. Clomipramine

Clomipramine is a tricyclic antidepressant. Clomipramine has been found to be effective in treating premature ejaculation. Clomipramine works by inhibiting the reuptake of serotonin. This helps to delay ejaculation.

Clomipramine can cause a number of side effects, including dry mouth, constipation, weight gain, and drowsiness. Clomipramine can also cause death when mixed with benzodiazepines. Because of this, Clomipramine is not recommended as a first-line treatment for premature ejaculation.

3. Codeine

Codeine is an opioid medication. Codeine is commonly used to treat pain, but can also be used to help control premature ejaculation. Codeine works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain. Codeine can also help to delay ejaculation by reducing the sensitivity of the penis.

Codeine is often abused, as it is an opioid medication. Codeine can be addictive and can lead to overdose and death. Because of this, most doctors won't recommend it for the treatment of premature ejaculation. It is better to stick to other options, such as behavioral therapy or SSRIs.

Where To Get Premature Ejaculation Pills

Phoenix is a telehealth service that exclusively helps men with men’s health issues like ED and hair loss. One of the most promising treatments for premature ejaculation is use of erectile dysfunction medications like Sildenafil and Tadalafil.

If you’re concerned about premature ejaculation, make an appointment with one of our board-certified physicians. We NEVER ask you to turn your camera on, and all our doctor’s visits are done with a text chat. Why wait? Make an appointment today.

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This blog post is for educational purposes only and does not constitute medical or other professional advice. Your specific circumstances should be discussed with a healthcare provider. All statements of opinion represent the writers' judgement at the time of publication and are subject to change. Phoenix and its affiliates provide no express or implied endorsements of third parties or their advice, opinions, information, products, or services.

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